1. Introduction to Differential Pressure Gauge

Importance in Cosmetics Manufacturing
In the cosmetics industry, production according to GMP – ISO 22716 standards requires not only compliant formulas and ingredients but also a strictly controlled production environment. One of the most critical factors is the pressure differential between cleanroom areas.

If differential pressure is not properly maintained:

  • Dust particles and microorganisms from supporting areas may infiltrate the main production zone.
  • The risk of cross-contamination between product batches increases significantly.
  • The entire production line may be disrupted, causing financial losses and damaging brand reputation.

To prevent these risks, cosmetic factories are required to install differential pressure gauges to monitor pressure between rooms.

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What is a Differential Pressure Gauge?
A differential pressure gauge is a device that measures and displays the pressure difference between two separate areas. For example: between the filling room and the hallway, or between the weighing room and the main production area.

This device is typically installed on partition walls, Airlock doors, or weighing booths, enabling engineers and QC staff to monitor real-time pressure status. As a result, factories can ensure that critical areas always maintain positive or negative pressure according to process requirements.

Operating Principle
A differential pressure gauge works by comparing the pressure between two spaces:

  • Analog/Magnehelic Gauge: Pressure is transmitted through tubing and displayed via a needle pointer.
  • Digital Gauge: Uses differential pressure sensors and displays results on a digital screen.
  • High-end models: Equipped with sound or light alarms when pressure exceeds set limits, allowing timely responses to protect the production environment.

Basic Types
Differential pressure gauges on the market are generally classified into three main groups:

  • Analog/Magnehelic Gauges
    • Advantages: Easy to use, durable, low cost.
    • Application: Suitable for hallways, changing rooms, or areas without alarm requirements.
  • Digital Gauges
    • Advantages: High accuracy, clear display, easy to integrate with central monitoring systems (BMS).
    • Application: Main production areas, QC labs, filling rooms.
  • Gauges with Alarm Integration
    • Advantages: Both measures pressure and provides alarm signals for deviations.
    • Application: Weighing rooms, packaging rooms, or areas requiring strict GMP – ISO 22716 compliance.

2. Latest Price List of Differential Pressure Gauges (2025)

Below are the common differential pressure gauges supplied by VCR for cosmetic factories, with measuring ranges and reference prices.

Product Name

Measuring Range

Key Features

Typical Applications

Reference Price (VND)

Differential Pressure Gauge MACROSCOPIC 0–60Pa

0 ~ 60 Pa

High sensitivity, analog display

Clean small rooms (Airlock, changing rooms)

850,000 – 1,200,000

Differential Pressure Gauge MACROSCOPIC -60 ~ +60Pa

-60 ~ +60 Pa

Measures both positive & negative pressure, durable, no power required

Weighing rooms, negative pressure areas

1,000,000 – 1,400,000

Differential Pressure Gauge MACROSCOPIC 0–250Pa

0 ~ 250 Pa

Clear display, low error rate

QC labs, small filling rooms

1,100,000 – 1,600,000

Differential Pressure Gauge MACROSCOPIC 0–500Pa

0 ~ 500 Pa

Compact design, most popular

Cosmetic production rooms, hallways

1,200,000 – 1,800,000

Differential Pressure Gauge MACROSCOPIC 0–750Pa

0 ~ 750 Pa

Wide range, high durability

Factories with large pressure differences, filling areas

1,300,000 – 1,900,000

Differential Pressure Gauge MACROSCOPIC 0–2500Pa

0 ~ 2500 Pa

Suitable for special environments, high load capacity

Pharmaceutical plants, drying rooms, high-pressure environments

1,800,000 – 2,500,000

Digital Differential Pressure Gauge Precise WL-YC

0 ~ 1000 Pa (customizable)

Digital display, low error, Reset/CLR button

Filling rooms, packaging rooms, BMS alarm integration

3,500,000 – 6,000,000

Price Notes

  • Prices include: CO, CQ certificates, and user manuals.
  • Excluded: VAT, transportation, installation, and calibration costs.
  • For turnkey GMP projects, customers will receive discounts for bulk purchases.

See more: A Guide to Differential Pressure Gauge Installation

3. Factors Affecting the Price of Differential Pressure Gauges

3.1. Type of Gauge

  • MACROSCOPIC Analog Gauges:
    Examples: 0–60Pa, -60~60Pa, 0–250Pa, 0–500Pa, 0–750Pa, 0–2500Pa.
    • Advantages: Easy to use, highly durable, no power supply required.
    • Price range: 850,000 – 2,500,000 VND depending on the model.
  • Precise WL-YC Digital Gauges:
    Equipped with an LCD screen for digital display, low error rate, and connectivity with monitoring systems.
    Suitable for filling rooms, packaging rooms, and areas requiring precise monitoring.
    • Higher price range: 3,500,000 – 6,000,000 VND.

3.2. Measuring Range

  • Small ranges such as 0–60Pa or 0–250Pa are more affordable, suitable for changing rooms or Airlocks.
  • Medium ranges such as 0–500Pa or 0–750Pa are commonly used in filling rooms and main production areas.
  • Wide ranges such as 0–2500Pa are more expensive due to higher durability and special design requirements for large pressure (e.g., drying rooms, specialized areas).

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3.3. Accuracy and Features

  • MACROSCOPIC: Approx. ±2% error, suitable for most cosmetic cleanroom monitoring needs.
  • Precise WL-YC (Digital): ±1% error, with Reset/CLR button and alarm support → higher price but meets GMP requirements effectively.

3.4. Brand & Origin

  • MACROSCOPIC: Widely used, affordable, chosen by many cosmetic factories for large-scale installation.
  • Precise (WL-YC): Premium digital line, higher price due to advanced measuring technology and smart alarm integration.

3.5. Additional Services

  • Purchasing only the basic gauge → lower cost.
  • Adding calibration, on-site installation, and extended warranty → increases the overall cost.
  • Cosmetic factories operating under GMP usually require periodic calibration → opting for a full-service package helps save long-term costs.

In summary, the price of a differential pressure gauge depends directly on:

  • Product type (MACROSCOPIC analog vs. Precise digital).
  • Measuring range (0–60Pa, 0–500Pa, 0–2500Pa, etc.).
  • Accuracy and additional features (basic – digital – with alarm).

See more: Unveiling the Significance of Differential Pressure Gauge in Pharmaceuticals Cleanrooms

4. Applications of Differential Pressure Gauges in Cosmetic Factories

In cosmetics manufacturing, maintaining proper cleanroom pressure is mandatory to prevent cross-contamination and ensure product quality. Differential pressure gauges are essential tools that allow engineers, QA, and QC teams to continuously monitor critical areas.

4.1. Filling and Packaging Rooms

  • Directly handle semi-finished or finished products.
  • Differential pressure gauges help maintain positive pressure compared to hallways and auxiliary rooms.
  • This prevents dust and microorganisms from entering, ensuring product sterility.

4.2. Weighing Rooms

  • The weighing process can generate fine dust or chemical vapors.
  • Differential pressure gauges ensure negative pressure, preventing dust from spreading to other areas.
  • Helps the factory meet GMP standards and reduces cross-contamination risks.

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4.3. Airlocks – Changing Rooms

  • Act as buffer zones between outside and clean areas.
  • Differential pressure gauges help maintain cascading pressure levels: corridor < Airlock < production room.
  • This mechanism prevents outside contaminants from entering the main production environment.

4.4. QC/QA Departments

  • Differential pressure gauges provide continuous monitoring data for quality control.
  • QC/QA teams can use this data in internal reports or during GMP – ISO 22716 audits.
  • Supports companies in demonstrating that their cleanroom system operates stably and meets international standards.

In short, differential pressure gauges are not just technical devices, but also the “invisible shield” protecting the quality of cosmetics throughout the entire production process.

See more: Differential Pressure Gauges for Air Filters - What do you already know?

5. FAQ – Frequently Asked Questions

1. Is a differential pressure gauge mandatory in cosmetic factories?

→ Yes. It is a standard device required to comply with GMP – ISO 22716. It helps control cleanroom pressure and prevents cross-contamination.

2. Should I choose an analog or a digital gauge?

→ If cost is the priority, the MACROSCOPIC analog gauge is the suitable choice.
→ If high accuracy, clear display, and alarm functions are needed, the Precise WL-YC digital series is recommended.

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3. How often should a differential pressure gauge be calibrated?

→ On average, every 6–12 months. For GMP cosmetic factories, calibration is usually aligned with internal audits and external assessments.

4. Can a differential pressure gauge be connected to the central monitoring system (BMS)?

→ Yes. Especially with digital models like Precise WL-YC, which support signal output for integration with BMS, enabling centralized monitoring across multiple areas.

5. Does VCR provide installation services and CO–CQ certificates?

→ Yes. VCR offers site survey, installation, and calibration services, and provides complete CO, CQ, and technical documentation to facilitate GMP acceptance.

6. Contact for Consultation & Detailed Quotation

Are you looking for differential pressure gauges for a cosmetic factory that complies with GMP – ISO 22716?
Don’t wait – contact VCR Cleanroom Equipment today to:

  • Get the latest 2025 detailed price list for all MACROSCOPIC and Precise WL-YC models.
  • Receive expert consultation to select the right model for each area: filling room, weighing room, Airlock, QC/QA.
  • Access full support for installation, calibration, and complete CO–CQ documents for GMP approval.
  • Enjoy special discounts for bulk orders or full-package cleanroom construction projects.

Contact now:

Hotline: 090.123.9008

Email: [email protected]

Website: https://donghochenhap.com/

Diep VCR