differential pressure gauge

Influence of differential pressure in cleanrooms

Mục Lục

In this article, we provide an overview of differential pressure – one of the key operating principles of cleanrooms. We outline what it is, how we measure it, and how differential pressure affects other conditions in cleanrooms.

Differential pressure in cleanrooms

Differential pressure refers to the difference in air pressure from one location to another within a system.

In cleanrooms, maintaining the right amount of differential pressure—either positive or negative—is essential to preventing contamination.

  • In positive differential pressure cleanrooms, the internal pressure is greater than the external pressure to prevent the ingress of any contaminants through any opening in the cleanroom.
  • In negative differential pressure cleanrooms, the external pressure is greater than the internal pressure to prevent the egress of any potentially harmful compounds contained within the cleanroom.

Combined with the appropriate temperature, humidity, and airflow level, proper differential pressure levels ensure both cleanroom designs work properly. It is essential to carefully measure and monitor pressure inside and outside of the cleanroom to confirm the differential pressure remains within the acceptable range.

To calculate the difference between two pressure points in the cleanroom (typically two inlet points), we offer Magrfhelic gauges for these applications. They provide accurate measurement of pressure, pressure differential, and vacuum to 2% of full scale. In addition to cleanrooms, typical use cases include automatic valves, control equipment, and gas-air ratio controls.

differential pressure in cleanroom

Cleanroom standards

The level of cleanliness required from a cleanroom depends on the applications. For this reason, cleanrooms are available in numerous classifications, each of which denotes a specific level attainable based on the number and size of contaminants with the given space.

The International Organization for Standardization (ISO) categorizes cleanrooms from ISO 1 to ISO 9, with ISO 1 having the fewest contaminants per square meter. In addition to the number of particulates, the size of particulates also plays a crucial role in ISO classification.

Contaminants are measured in microns, from 1μm to 5μm, with different cleanrooms offering different filtration capacities for each size. For example, clean rooms with HEPA filters remove particulates as small as 0.3μm with 99.99% efficiency rates, while cleanrooms with ultra-low particulate filters remove particulates as small as 0.12μm with an efficiency rate of 99.999%.

The effectiveness of the mechanisms that facilitate cleanroom operations—including the filters—depends on many factors remaining within acceptable levels. These factors include pressure, temperature, humidity, and airflow, all of which can help the maintenance of proper cleanliness levels.

Vietnam Cleanroom Equipment (VCR) specializes in providing cleanroom equipment for construction contractors. We provide high-quality products with competitive prices and large quantities nationwide. The equipment includes:

Differential pressure gauge, FFU Fan Filter Unit, Pass box, Clean room air filter, HEPA box, Clean room dispensing booth, cleanroom steel door, Isolator cabinet, and other equipment

For details, please refer to Vietnam cleanroom equipment official website


Related Posts

error: Content is protected !!
Scroll to Top
Phòng Sạch

Phòng sạch trong sản xuất dược phẩm theo tiêu chuẩn GMP